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| Kalegari,Milena; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari; Lordello,Ana Luísa Lacava; Lima,Cristina Peitz de; Miyazaki,Cristina Mayumi Sasaki; Zanin,Sandra Maria Warumby; Verdam,Maria Christina dos Santos; Miguel,Obdulio Gomes. |
| Most active plants are toxic at high doses and it is therefore important to investigate the preliminary toxicity of plant extracts. The Rourea induta species is a potential drug with no phytochemical or biological studies registered in the literature. Thus, a phytochemical study and a toxicity analysis of the ethanolic extract obtained from the leaves of Rourea induta Planch., Connaraceae, was run. A long chain hydrocarbon, n-tetracosane, and four flavonoids were identified: quercetin, and three glycosylated derivates, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-β-xyloside and quercetin-3-O-β-galactoside. This is the first time these have been isolated in this species. The structures were elucidated by 13C NMR, ¹H NMR, UV and IR spectroscopy. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rourea induta/phytochemistry; Connaraceae/phytochemistry; Flavonoids; N-tetracosane; Plant extracts/toxicity. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300023 |
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